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Number of iterations until stability. This represents the following graph structure. We generated benchmark networks in the following way. Community detection in complex networks using extremal optimization. For example, for the Web of Science network, the first iteration takes about 110120 seconds, while subsequent iterations require about 40 seconds. The constant Potts model (CPM), so called due to the use of a constant value in the Potts model, is an alternative objective function for community detection. In general, Leiden is both faster than Louvain and finds better partitions. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. When iterating Louvain, the quality of the partitions will keep increasing until the algorithm is unable to make any further improvements. The leidenalg package facilitates community detection of networks and builds on the package igraph. Communities in \({\mathscr{P}}\) may be split into multiple subcommunities in \({{\mathscr{P}}}_{{\rm{refined}}}\). Instead, a node may be merged with any community for which the quality function increases. & Girvan, M. Finding and evaluating community structure in networks. PubMed Central Phys. wrote the manuscript. Theory Exp. Even though clustering can be applied to networks, it is a broader field in unsupervised machine learning which deals with multiple attribute types. Contrary to what might be expected, iterating the Louvain algorithm aggravates the problem of badly connected communities, as we will also see in our experimental analysis. ADS Hence, the community remains disconnected, unless it is merged with another community that happens to act as a bridge. E 69, 026113, https://doi.org/10.1103/PhysRevE.69.026113 (2004). Once aggregation is complete we restart the local moving phase, and continue to iterate until everything converges down to one node. Iterating the Louvain algorithm can therefore be seen as a double-edged sword: it improves the partition in some way, but degrades it in another way. The algorithm is described in pseudo-code in AlgorithmA.2 in SectionA of the Supplementary Information. Soft Matter Phys. We now consider the guarantees provided by the Leiden algorithm. CAS You signed in with another tab or window. Moreover, the deeper significance of the problem was not recognised: disconnected communities are merely the most extreme manifestation of the problem of arbitrarily badly connected communities. While smart local moving and multilevel refinement can improve the communities found, the next two improvements on Louvain that Ill discuss focus on the speed/efficiency of the algorithm. import leidenalg as la import igraph as ig Example output. First iteration runtime for empirical networks. In the first step of the next iteration, Louvain will again move individual nodes in the network. Acad. J. MathSciNet Article In fact, although it may seem that the Louvain algorithm does a good job at finding high quality partitions, in its standard form the algorithm provides only one guarantee: the algorithm yields partitions for which it is guaranteed that no communities can be merged. As can be seen in Fig. Rev. An overview of the various guarantees is presented in Table1. The horizontal axis indicates the cumulative time taken to obtain the quality indicated on the vertical axis. This phenomenon can be explained by the documented tendency KMeans has to identify equal-sized , combined with the significant class imbalance associated with the datasets having more than 8 clusters (Table 1). In this stage we essentially collapse communities down into a single representative node, creating a new simplified graph. 63, 23782392, https://doi.org/10.1002/asi.22748 (2012). As the use of clustering is highly depending on the biological question it makes sense to use several approaches and algorithms. V.A.T. Traag, V. A. In the most difficult case (=0.9), Louvain requires almost 2.5 days, while Leiden needs fewer than 10 minutes. Scientific Reports (Sci Rep) * (2018). 2007. CPM is defined as. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate. Raghavan, U., Albert, R. & Kumara, S. Near linear time algorithm to detect community structures in large-scale networks. Importantly, the number of communities discovered is related only to the difference in edge density, and not the total number of nodes in the community. Is modularity with a resolution parameter equivalent to leidenalg.RBConfigurationVertexPartition? For each network, we repeated the experiment 10 times. Runtime versus quality for benchmark networks. For example, the red community in (b) is refined into two subcommunities in (c), which after aggregation become two separate nodes in (d), both belonging to the same community. The aggregate network is created based on the partition \({{\mathscr{P}}}_{{\rm{refined}}}\). Nevertheless, depending on the relative strengths of the different connections, these nodes may still be optimally assigned to their current community. The quality improvement realised by the Leiden algorithm relative to the Louvain algorithm is larger for empirical networks than for benchmark networks. There is an entire Leiden package in R-cran here This will compute the Leiden clusters and add them to the Seurat Object Class. However, Leiden is more than 7 times faster for the Live Journal network, more than 11 times faster for the Web of Science network and more than 20 times faster for the Web UK network. Leiden is the most recent major development in this space, and highlighted a flaw in the original Louvain algorithm (Traag, Waltman, and Eck 2018). If material is not included in the articles Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. As the problem of modularity optimization is NP-hard, we need heuristic methods to optimize modularity (or CPM). ADS Internet Explorer). However, in the case of the Web of Science network, more than 5% of the communities are disconnected in the first iteration. In this case we know the answer is exactly 10. The nodes that are more interconnected have been partitioned into separate clusters. At some point, node 0 is considered for moving. The speed difference is especially large for larger networks. The algorithm optimises a quality function such as modularity or CPM in two elementary phases: (1) local moving of nodes; and (2) aggregation of the network. Sci Rep 9, 5233 (2019). The Leiden algorithm is typically iterated: the output of one iteration is used as the input for the next iteration. Discov. The Leiden algorithm is considerably more complex than the Louvain algorithm. An aggregate network (d) is created based on the refined partition, using the non-refined partition to create an initial partition for the aggregate network. It therefore does not guarantee -connectivity either. This will compute the Leiden clusters and add them to the Seurat Object Class. In addition, a node is merged with a community in \({{\mathscr{P}}}_{{\rm{refined}}}\) only if both are sufficiently well connected to their community in \({\mathscr{P}}\). For the results reported below, the average degree was set to \(\langle k\rangle =10\). Computer Syst. Ph.D. thesis, (University of Oxford, 2016). Duch, J. Blondel, V. D., Guillaume, J.-L., Lambiotte, R. & Lefebvre, E. Fast unfolding of communities in large networks. That is, one part of such an internally disconnected community can reach another part only through a path going outside the community. IEEE Trans. 5, for lower values of the partition is well defined, and neither the Louvain nor the Leiden algorithm has a problem in determining the correct partition in only two iterations. As shown in Fig. These nodes can be approximately identified based on whether neighbouring nodes have changed communities. DBSCAN Clustering Explained Detailed theorotical explanation and scikit-learn implementation Clustering is a way to group a set of data points in a way that similar data points are grouped together. Slider with three articles shown per slide. In other words, modularity may hide smaller communities and may yield communities containing significant substructure. The random component also makes the algorithm more explorative, which might help to find better community structures. We gratefully acknowledge computational facilities provided by the LIACS Data Science Lab Computing Facilities through Frank Takes. We abbreviate the leidenalg package as la and the igraph package as ig in all Python code throughout this documentation. Phys. In the meantime, to ensure continued support, we are displaying the site without styles J. A. Finding community structure in networks using the eigenvectors of matrices. Sci. Eng. Furthermore, if all communities in a partition are uniformly -dense, the quality of the partition is not too far from optimal, as shown in SectionE of the Supplementary Information. CPM has the advantage that it is not subject to the resolution limit. The count of badly connected communities also included disconnected communities. After the refinement phase is concluded, communities in \({\mathscr{P}}\) often will have been split into multiple communities in \({{\mathscr{P}}}_{{\rm{refined}}}\), but not always. Traag, V.A., Waltman, L. & van Eck, N.J. From Louvain to Leiden: guaranteeing well-connected communities. Badly connected communities. 2(a). This should be the first preference when choosing an algorithm. The Louvain local moving phase consists of the following steps: This process is repeated for every node in the network until no further improvement in modularity is possible. Hence, no further improvements can be made after a stable iteration of the Louvain algorithm. The corresponding results are presented in the Supplementary Fig. The percentage of disconnected communities is more limited, usually around 1%. The idea of the refinement phase in the Leiden algorithm is to identify a partition \({{\mathscr{P}}}_{{\rm{refined}}}\) that is a refinement of \({\mathscr{P}}\). 4. The algorithm is run iteratively, using the partition identified in one iteration as starting point for the next iteration. The classic Louvain algorithm should be avoided due to the known problem with disconnected communities. The Leiden algorithm is considerably more complex than the Louvain algorithm. In particular, benchmark networks have a rather simple structure. Louvain pruning keeps track of a list of nodes that have the potential to change communities, and only revisits nodes in this list, which is much smaller than the total number of nodes. However, so far this problem has never been studied for the Louvain algorithm. Data Eng. Ronhovde, Peter, and Zohar Nussinov. To use Leiden with the Seurat pipeline for a Seurat Object object that has an SNN computed (for example with Seurat::FindClusters with save.SNN = TRUE). N.J.v.E. Complex brain networks: graph theoretical analysis of structural and functional systems. In other words, communities are guaranteed to be well separated. V. A. Traag. The docs are here. We show that this algorithm has a major defect that largely went unnoticed until now: the Louvain algorithm may yield arbitrarily badly connected communities. For the Amazon, DBLP and Web UK networks, Louvain yields on average respectively 23%, 16% and 14% badly connected communities. Unsupervised clustering of cells is a common step in many single-cell expression workflows. The phase one loop can be greatly accelerated by finding the nodes that have the potential to change community and only revisit those nodes. & Clauset, A. The value of the resolution parameter was determined based on the so-called mixing parameter 13. As far as I can tell, Leiden seems to essentially be smart local moving with the additional improvements of random moving and Louvain pruning added. Based on this partition, an aggregate network is created (c). As we will demonstrate in our experimental analysis, the problem occurs frequently in practice when using the Louvain algorithm. This function takes a cell_data_set as input, clusters the cells using . Even worse, the Amazon network has 5% disconnected communities, but 25% badly connected communities. Clustering with the Leiden Algorithm in R This package allows calling the Leiden algorithm for clustering on an igraph object from R. See the Python and Java implementations for more details: https://github.com/CWTSLeiden/networkanalysis https://github.com/vtraag/leidenalg Install The two phases are repeated until the quality function cannot be increased further. In an experiment containing a mixture of cell types, each cluster might correspond to a different cell type. Phys. Mech. Rev. I tracked the number of clusters post-clustering at each step. Hence, the Leiden algorithm effectively addresses the problem of badly connected communities. Class wrapper based on scanpy to use the Leiden algorithm to directly cluster your data matrix with a scikit-learn flavor. The increase in the percentage of disconnected communities is relatively limited for the Live Journal and Web of Science networks. Eng. We also suggested that the Leiden algorithm is faster than the Louvain algorithm, because of the fast local move approach. Leiden is both faster than Louvain and finds better partitions. Zenodo, https://doi.org/10.5281/zenodo.1469357 https://github.com/vtraag/leidenalg. Rev. Google Scholar. Google Scholar. CAS Source Code (2018). This is well illustrated by figure 2 in the Leiden paper: When a community becomes disconnected like this, there is no way for Louvain to easily split it into two separate communities. A partition of clusters as a vector of integers Examples After each iteration of the Leiden algorithm, it is guaranteed that: In these properties, refers to the resolution parameter in the quality function that is optimised, which can be either modularity or CPM. 2016. Community detection can then be performed using this graph. At each iteration all clusters are guaranteed to be connected and well-separated. Each point corresponds to a certain iteration of an algorithm, with results averaged over 10 experiments. Google Scholar. For each community in a partition that was uncovered by the Louvain algorithm, we determined whether it is internally connected or not. We find that the Leiden algorithm is faster than the Louvain algorithm and uncovers better partitions, in addition to providing explicit guarantees. We provide the full definitions of the properties as well as the mathematical proofs in SectionD of the Supplementary Information. The inspiration for this method of community detection is the optimization of modularity as the algorithm progresses. 9, the Leiden algorithm also performs better than the Louvain algorithm in terms of the quality of the partitions that are obtained. Ayan Sinha, David F. Gleich & Karthik Ramani, Marinka Zitnik, Rok Sosi & Jure Leskovec, Zhenqi Lu, Johan Wahlstrm & Arye Nehorai, Natalie Stanley, Roland Kwitt, Peter J. Mucha, Scientific Reports We applied the Louvain and the Leiden algorithm to exactly the same networks, using the same seed for the random number generator. To address this problem, we introduce the Leiden algorithm. Percentage of communities found by the Louvain algorithm that are either disconnected or badly connected compared to percentage of badly connected communities found by the Leiden algorithm. Random moving is a very simple adjustment to Louvain local moving proposed in 2015 (Traag 2015). Communities may even be disconnected. The differences are not very large, which is probably because both algorithms find partitions for which the quality is close to optimal, related to the issue of the degeneracy of quality functions29. o CLIQUE (Clustering in Quest): - CLIQUE is a combination of density-based and grid-based clustering algorithm. Cluster your data matrix with the Leiden algorithm. The reasoning behind this is that the best community to join will usually be the one that most of the nodes neighbors already belong to. Note that if Leiden finds subcommunities, splitting up the community is guaranteed to increase modularity. In this new situation, nodes 2, 3, 5 and 6 have only internal connections. Nature 433, 895900, https://doi.org/10.1038/nature03288 (2005). performed the experimental analysis. ADS This amounts to a clustering problem, where we aim to learn an optimal set of groups (communities) from the observed data. The refined partition \({{\mathscr{P}}}_{{\rm{refined}}}\) is obtained as follows. This is not the case when nodes are greedily merged with the community that yields the largest increase in the quality function. Google Scholar. (2) and m is the number of edges. We will use sklearns K-Means implementation looking for 10 clusters in the original 784 dimensional data. 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This contrasts to benchmark networks, for which Leiden often converges after a few iterations. This is very similar to what the smart local moving algorithm does. Get the most important science stories of the day, free in your inbox. This algorithm provides a number of explicit guarantees. Hence, by counting the number of communities that have been split up, we obtained a lower bound on the number of communities that are badly connected. With one exception (=0.2 and n=107), all results in Fig. Importantly, the problem of disconnected communities is not just a theoretical curiosity. Speed of the first iteration of the Louvain and the Leiden algorithm for benchmark networks with increasingly difficult partitions (n=107). J. Stat. Soft Matter Phys. Trying to fix the problem by simply considering the connected components of communities19,20,21 is unsatisfactory because it addresses only the most extreme case and does not resolve the more fundamental problem. Traag, V A. b, The elephant graph (in a) is clustered using the Leiden clustering algorithm 51 (resolution r = 0.5). Faster unfolding of communities: Speeding up the Louvain algorithm. Newman, M E J, and M Girvan. Nodes 06 are in the same community. Importantly, the first iteration of the Leiden algorithm is the most computationally intensive one, and subsequent iterations are faster. There was a problem preparing your codespace, please try again. This is similar to what we have seen for benchmark networks. Article We name our algorithm the Leiden algorithm, after the location of its authors. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in One of the best-known methods for community detection is called modularity3. Note that the object for Seurat version 3 has changed. One may expect that other nodes in the old community will then also be moved to other communities. In subsequent iterations, the percentage of disconnected communities remains fairly stable. For example an SNN can be generated: For Seurat version 3 objects, the Leiden algorithm has been implemented in the Seurat version 3 package with Seurat::FindClusters and algorithm = "leiden"). E 70, 066111, https://doi.org/10.1103/PhysRevE.70.066111 (2004). Sci. However, values of within a range of roughly [0.0005, 0.1] all provide reasonable results, thus allowing for some, but not too much randomness. The algorithm then locally merges nodes in \({{\mathscr{P}}}_{{\rm{refined}}}\): nodes that are on their own in a community in \({{\mathscr{P}}}_{{\rm{refined}}}\) can be merged with a different community. Phys. Luecken, M. D. Application of multi-resolution partitioning of interaction networks to the study of complex disease. 2015. In fact, by implementing the refinement phase in the right way, several attractive guarantees can be given for partitions produced by the Leiden algorithm. J. Exp. The nodes are added to the queue in a random order. We here introduce the Leiden algorithm, which guarantees that communities are well connected. Edges were created in such a way that an edge fell between two communities with a probability and within a community with a probability 1. In that case, some optimal partitions cannot be found, as we show in SectionC2 of the Supplementary Information. and L.W. Clauset, A., Newman, M. E. J. Note that this code is . Runtime versus quality for empirical networks. A tag already exists with the provided branch name. A community size of 50 nodes was used for the results presented below, but larger community sizes yielded qualitatively similar results. To address this important shortcoming, we introduce a new algorithm that is faster, finds better partitions and provides explicit guarantees and bounds. After a stable iteration of the Leiden algorithm, the algorithm may still be able to make further improvements in later iterations. That is, no subset can be moved to a different community. Bullmore, E. & Sporns, O. It maximizes a modularity score for each community, where the modularity quantifies the quality of an assignment of nodes to communities. This is not too difficult to explain. Rev. This commit does not belong to any branch on this repository, and may belong to a fork outside of the repository. SPATA2 currently offers the functions findSeuratClusters (), findMonocleClusters () and findNearestNeighbourClusters () which are wrapper around widely used clustering algorithms. It was originally developed for modularity optimization, although the same method can be applied to optimize CPM. 6 show that Leiden outperforms Louvain in terms of both computational time and quality of the partitions. & Moore, C. Finding community structure in very large networks. bioRxiv, https://doi.org/10.1101/208819 (2018). The property of -connectivity is a slightly stronger variant of ordinary connectivity. Figure4 shows how well it does compared to the Louvain algorithm. We first applied the Scanpy pipeline, including its clustering method (Leiden clustering), on the PBMC dataset. Communities in Networks. E 92, 032801, https://doi.org/10.1103/PhysRevE.92.032801 (2015). 69 (2 Pt 2): 026113. http://dx.doi.org/10.1103/PhysRevE.69.026113. We keep removing nodes from the front of the queue, possibly moving these nodes to a different community. In this case we can solve one of the hard problems for K-Means clustering - choosing the right k value, giving the number of clusters we are looking for. 2(b). Each point corresponds to a certain iteration of an algorithm, with results averaged over 10 experiments. The PyPI package leiden-clustering receives a total of 15 downloads a week. where >0 is a resolution parameter4. USA 104, 36, https://doi.org/10.1073/pnas.0605965104 (2007). Because the percentage of disconnected communities in the first iteration of the Louvain algorithm usually seems to be relatively low, the problem may have escaped attention from users of the algorithm. Elect. Work fast with our official CLI. Moreover, Louvain has no mechanism for fixing these communities. A community is subset optimal if all subsets of the community are locally optimally assigned. 2010. Phys. S3. If nothing happens, download Xcode and try again. E 74, 016110, https://doi.org/10.1103/PhysRevE.74.016110 (2006). This is the crux of the Leiden paper, and the authors show that this exact problem happens frequently in practice. Many Git commands accept both tag and branch names, so creating this branch may cause unexpected behavior. All authors conceived the algorithm and contributed to the source code. Google Scholar. Not. Natl. The algorithm may yield arbitrarily badly connected communities, over and above the well-known issue of the resolution limit14. In particular, in an attempt to find better partitions, multiple consecutive iterations of the algorithm can be performed, using the partition identified in one iteration as starting point for the next iteration. Such a modular structure is usually not known beforehand. In practical applications, the Leiden algorithm convincingly outperforms the Louvain algorithm, both in terms of speed and in terms of quality of the results, as shown by the experimental analysis presented in this paper. Int. 2 represent stronger connections, while the other edges represent weaker connections. However, for higher values of , Leiden becomes orders of magnitude faster than Louvain, reaching 10100 times faster runtimes for the largest networks. In a stable iteration, the partition is guaranteed to be node optimal and subpartition -dense. It is a directed graph if the adjacency matrix is not symmetric. The algorithm then moves individual nodes in the aggregate network (e). Scaling of benchmark results for network size. Wolf, F. A. et al. As can be seen in the figure, Louvain quickly reaches a state in which it is unable to find better partitions. Zenodo, https://doi.org/10.5281/zenodo.1466831 https://github.com/CWTSLeiden/networkanalysis.